Ornipressina
composto chimico
L'ornipressina è un vasocostrittore[1][2] e antiemorragico.
| Ornipressina | |
|---|---|
 | |
| Nome IUPAC | |
| (2S)-N-[(2S)-5-Amino-1-[(2-amino-2-oxoethyl)amino]- 1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)- 19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl] -6,9,12,15,18-pentaoxo-13-(phenylmethyl)1,2-dithia-5,8,11,14,17- pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide | |
| Caratteristiche generali | |
| Formula bruta o molecolare | C45H63N13O12S2 |
| Numero CAS | |
| Numero EINECS | 222-253-8 |
| Codice ATC | H01 |
| PubChem | 14257660 |
| DrugBank | DBDB13464 |
| SMILES | C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN)C(=O)NCC(=O)N |
| Indicazioni di sicurezza | |
Note
modifica- ^ H. Fruhstofer, M.D., M. Heisler, M.D., Dose-response relation of ornipressin with regard to vasoconstriction in human skin, in Br. J. Anaesth., vol. 73, n. 2, 1994, pp. 220–224, DOI:10.1093/bja/73.2.220.
- ^ Marc De Kock, MD, Pierre-Francois Laterre, MD, Patricia Andruetto, MD, Lionel Vanderessen, MD, Sylvie Dekrom, MD, Bernard Vanderick, MD and Patricia Lavand’homme, MD, Ornipressin (Por 8): An Efficient Alternative to Counteract Hypotension During Combined General/Epidural Anesthesia, in Anesthesia & Analgesia, vol. 90, n. 6, June 2000, pp. 1301–1307, DOI:10.1097/00000539-200006000-00008.
